Lipids and Lipid Derivatives
Medchemexpress LLC MAIT-203 (acetate) | 99.1% | 2577.90 | 25 MG
MAIT-203 acetate is a cyclopentyalanin-derived peptidomimetic that potently inhibits the interaction of adenomatous polyposis coli (APC) and Asef (RhoGEF4), but not APC-Sam68 or APC-striatin interactions. It binds APC-ARM with a Ki value of 0.015 μM and a Kd value of 0.036 μΜ. This compound significantly represses the migration and invasion of colorectal cancer cells.
- Potently inhibits APC-Asef interaction
- Binds APC-ARM with a Ki value of 0.015 μM and a Kd value of 0.036 μΜ
- Significantly represses migration and invasion of colorectal cancer cells
- Reduces Asef-APC interaction in HEK293T cells
- Attenuates SW480 and HCT116 cell migration
- Decreases the active form of CDC42
Sigma Aldrich Fine Chemicals Biosciences U-73343 | 142878-12-4 | MFCD00211221 | 5MG
U-73343 | Purity: >=98% (HPLC) | Mol Wt: 466.66 | 142878-12-4 | MFCD00211221 | 5MG
Medchemexpress LLC Estradiol benzoate (standard) | 50-50-0 | 99.7% | 50 MG
Estradiol benzoate (Standard) is an analytical standard intended for research and analytical applications. It acts as an HBx protein inhibitor, inhibiting androgen and hepatitis B virus (HBV) transcription and replication. Additionally, it demonstrates antifertility effects, anti-Toxoplasma gondii activity, and can enhance memory behavior in Ovariectomy (Ovx) female mice. This analytical standard is commonly used in qualitative, quantitative, and methodological research experiments, including HPLC, GC, and MS.
- Intended for research and analytical applications.
- Inhibits HBx protein, androgen, and hepatitis B virus (HBV) transcription and replication.
- Demonstrates antifertility effects.
- Shows anti-Toxoplasma gondii activity.
- Improves memory behavior in Ovariectomy (Ovx) female mice.
- Suitable for HPLC, GC, and MS research experiments.
Medchemexpress LLC Estradiol benzoate | 50-50-0 | 99.9% | 25 MG
Estradiol benzoate is an HBx protein inhibitor that inhibits androgen and hepatitis B virus (HBV) transcription and replication. It demonstrates antifertility effects and anti-Toxoplasma gondii activity.
- Improves memory behavior in ovariectomy (Ovx) female mice
- Appearance: solid, white to off-white
- For research use only
Cambridge Isotope Laboratories DL-Estrone 3-methyl ether (13 14 15 16 17 18-13C6 99%) 0 1 mg
DL-Estrone 3-methyl ether (13 14 15 16 17 18-13C6 99%) 0 1 mg
Medchemexpress LLC ACTH (11-24) acetate | 99.88% | 1652.04 | 10 MG
ACTH (11-24) (acetate) is an adrenocorticotropic hormone (ACTH) receptor antagonist. It is a fragment of adrenocorticotropic and induces cortisol release. This compound can be used for research of the central nervous system. In vitro, ACTH (11-24) (acetate) elicits cortisol secretion submaximally in freshly dispersed or cultured beef adrenal cortical cells, and in vivo, it has slight influences on circulating plasma corticosterone values and on fighting behavior.
- Adrenocorticotropic hormone (ACTH) receptor antagonist
- Induces cortisol release
- Suitable for research of the central nervous system
- Purity of 99.88%
- Molecular weight of 1652.04 (free base)
Medchemexpress LLC Norethindrone acetate | 51-98-9 | 99.47% | 50 MG
Norethindrone acetate (Standard) is the analytical standard of Norethindrone acetate, intended for research and analytical applications. It is a female hormone used for the research of endometriosis. It also functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. This product is for research use only and not sold to patients.
- Analytical standard, reference standard supplied assay.
- Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Molecular weight: 340.46
- Formula: C₂₂H₂₈O₃
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC Paramethasone acetate | 1597-82-6 | MFCD00200359 | 98.0% | 434.50 g·mol⁻¹ | C24H31FO6 | 5 MG
Paramethasone acetate is a synthetic glucocorticoid acetate ester supplied for research use. It shows anti-inflammatory and immunosuppressant activity and is provided as a solid reagent for laboratory and analytical applications. Safety data and handling information are available in the SDS and supporting documentation.
- Exhibits anti-inflammatory and immunosuppressant activity.
- Acetate ester form suitable for standard biochemical assays.
- High purity (98.0%) for reproducible research results.
- Solid, white to light yellow appearance simplifies storage and handling.
- Available in small research quantities (e.g., 5 mg).
- SDS and safety documentation available for laboratory compliance.
Medchemexpress LLC Velmupressin acetate | 1647120-04-4 | 99.5% | 1006.63 | 10 MG
Velmupressin acetate is a potent, selective, and short-acting peptidic V2 receptor (V2R) agonist. It exhibits high affinity for both human (hV2R) and rat (rV2R) V2 receptors, with EC50s of 0.07 nM and 0.02 nM respectively. This product is intended for research purposes only.
- Potent and selective V2 receptor agonist
- Short-acting peptidic compound
- High affinity for human and rat V2 receptors
- For research purposes only
Medchemexpress LLC Velmupressin acetate | 1647120-04-4 | 1006.64 g/mol | 1 MG
Velmupressin acetate is a potent, selective, and short-acting peptidic V2 receptor (V2R) agonist. It exhibits EC50 values of 0.07 nM for human V2R (hV2R) and 0.02 nM for rat V2R (rV2R). This product is stable under recommended storage conditions and is not classified as a hazardous substance or mixture according to safety data.
- Potent, selective, and short-acting peptidic V2 receptor (V2R) agonist
- EC50 values of 0.07 nM for human V2R (hV2R)
- EC50 values of 0.02 nM for rat V2R (rV2R)
- Stable under recommended storage conditions
- Not a hazardous substance or mixture
- For research use only
Apexbio Technology LLC Deoxycorticosterone acetate 56-47-3 10mM (in 1mL DMSO)
Deoxycorticosterone acetate (56-47-3) is a small-molecule agonist targeting mineralocorticoid receptors (MR) It is designed to activate MR thereby regulating renal sodium reabsorption and potassium excretion Deoxycorticosterone acetate exerts its biological activity primarily through interaction with cytoplasmic mineralocorticoid receptors leading to nuclear translocation and modulation of electrolyte balance Typical IC50 values associated with its mineralocorticoid receptor binding affinity have been reported in the nanomolar range Based on these pharmacological properties Deoxycorticosterone acetate holds research potential in studies of electrolyte balance adrenal insufficiency modeling and the pathophysiology of hypertension as well as models investigating mineralocorticoid receptor-dependent signaling and renal or cardiovascular physiology
Apexbio Technology LLC Deoxycorticosterone acetate 56-47-3 50mg
Deoxycorticosterone acetate (56-47-3) is a small-molecule agonist targeting mineralocorticoid receptors (MR) It is designed to activate MR thereby regulating renal sodium reabsorption and potassium excretion Deoxycorticosterone acetate exerts its biological activity primarily through interaction with cytoplasmic mineralocorticoid receptors leading to nuclear translocation and modulation of electrolyte balance Typical IC50 values associated with its mineralocorticoid receptor binding affinity have been reported in the nanomolar range Based on these pharmacological properties Deoxycorticosterone acetate holds research potential in studies of electrolyte balance adrenal insufficiency modeling and the pathophysiology of hypertension as well as models investigating mineralocorticoid receptor-dependent signaling and renal or cardiovascular physiology
Apexbio Technology LLC Medroxyprogesterone 520-85-4 50mg
Medroxyprogesterone (CAS 520-85-4) is a small-molecule agonist targeting the progesterone receptor It is designed to activate progesterone receptor-mediated intracellular signaling pathways thereby regulating cellular proliferation Medroxyprogesterone exerts its biological activity primarily through agonism of the progesterone receptor modulating pathways such as PI3K/Akt signaling In preclinical mouse models medroxyprogesterone demonstrates inhibitory activity on atherosclerotic lesion formation Based on these pharmacological properties medroxyprogesterone holds research potential in the study of progesterone receptor-mediated biological processes cellular proliferation and vascular pathology